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1. **What is Opana ER?**
– Opana ER is a prescription medication that contains **oxymorphone**, an opioid analgesic.
– It is used to treat **moderate to severe pain** in patients who need around-the-clock pain management.
– The “ER” refers to the **extended-release** formulation, which allows for prolonged pain relief over an extended period.

2. **Mechanism of Action:**
– Opana ER works by binding to **opioid receptors** in the brain and spinal cord, blocking pain signals.
– This helps reduce the perception of pain and provides relief.

3. **Indications:**
– It is prescribed for individuals with **chronic pain**, especially for those who need continuous pain relief.
– Not suitable for use in **acute pain** or **postoperative pain** due to its long-acting nature.

4. **Dosage and Administration:**
– Opana ER should be taken **exactly as prescribed**, usually once or twice daily.
– The medication must be swallowed whole, without crushing, chewing, or breaking, to prevent the risk of a dangerous overdose.

5. **Side Effects:**
– Common side effects include **nausea**, **dizziness**, **constipation**, and **headache**.
– Serious side effects may include **respiratory depression**, **low blood pressure**, **bradycardia**, and **addiction**.
– Overdose can be fatal, so it’s crucial to follow the prescribed dosage.

6. **Precautions:**
– Opana ER should be used with caution in patients with a history of **substance abuse**, **respiratory disorders**, or **liver problems**.
– It is not recommended for use in patients who are **pregnant** or **breastfeeding** unless absolutely necessary.

7. **Risk of Dependence:**
– As an opioid, Opana ER carries a high risk of **dependence, abuse**, and **tolerance**. Regular monitoring by a healthcare provider is necessary.

8. **Discontinuation:**
– Sudden discontinuation may lead to **withdrawal symptoms**, so it should be tapered under a doctor’s guidance.

9. **Important Notes:**
– Opana ER is highly regulated due to its potential for abuse and addiction.
– It should only be used when no other treatment options are effective for pain management.